3 ith +4, thus all NH and C=O groups in an -helix are linked with hydrogen bonds except for the first NH (the N -terminus) and the last CO group (the C -terminus) of the -helix (Figure 1.1 ) (Perez de Vega et al. 1.2 Protein-Protein Interactions (PPIs) The -helix can be involved in many proteinprotein interactions (PPIs) through the. The Savirs in the Caucasus 19 9 mi nd the re ader t hat he beca me the sole l ea der of the Hun nish u nion af te r vio lently oust ing his o w n brother, B leda, in 44 5.

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